Isotopically Labeled Compounds
Medchemexpress LLC Dodecanoic-1-13C acid | 93639-08-8 | 99.8% | 201.31 g·mol⁻1 | C11(13C)H24O2 | 25mg
Lauric acid-13C is the 13C labeled Lauric acid Lauric acid is a middle chain-free fatty acid with strong bactericidal properties The EC50s for P acnes S aureus S epidermidis are 2 6 4 g/mL respectively
Medchemexpress LLC D-phenylalanine-d5 | 362049-55-6 | MFCD01861577 | 99.9% | 170.22 | C9H6D5NO2 | 5mg
D-Phenylalanine-d5 is the deuterium labeled D-Phenylalanine D-Phenylalanine is the synthetic dextro isomer of phenylalanine D-Phenylalanine inhibits biofilm development of Pseudoalteromonas sp SC2014[1]
Sigma Aldrich Fine Chemicals Biosciences Equilin-2,4,16,16-d4 98 atom % D | 285979-79-5 | MFCD01074212 | 100MG
Equilin-2,4,16,16-d4 98 atom % D | Mol Wt: 272.37 | 285979-79-5 | MFCD01074212 | 100MG
Medchemexpress LLC Flubendazole-d3 | 1173021-08-3 | 96.00% | 1 MG
Flubendazole-d3 is a deuterium-labeled version of Flubendazole, a safe and effective anthelmintic agent used in humans, rodents, and ruminants. It demonstrates anticancer activities by inhibiting microtubule function, inducing p53-mediated apoptosis, and arresting the G2/M cell cycle. Deuterium substitution in drug molecules can impact their pharmacokinetic and metabolic profiles.
- Deuterium labeled version of Flubendazole
- Safe and effective anthelmintic agent
- Exhibits anticancer activities via microtubule inhibition
- Induces p53-mediated apoptosis
- Arrests G2/M cell cycle
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis (e.g., NMR, GC-MS, LC-MS)
Medchemexpress LLC Adenine-13C | 86967-48-8 | 99.1% | 1 MG
Adenine-13C is the 13C labeled Adenine. As 6-Aminopurine, it is a purine and one of the four nucleobases found in the nucleic acid of DNA and RNA. This compound plays a significant role in biochemistry, particularly in cellular respiration, forming both ATP and cofactors (NAD and FAD), and protein synthesis.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Lactate-d4 sodium | 344299-52-1 | 99.0% | 5 MG
Lactic acid-d4 sodium (60% in water) is a deuterium-labeled form of lactic acid sodium. The unlabeled compound is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator that induces lysine residue lactylation. It serves as a glycolysis end-product, bridging glycolysis and oxidative phosphorylation. It is also recognized as an oncometabolite with an immune-protective role in anti-tumor immunity and possesses antimicrobial activity, making it suitable as a food preservative.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration has potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Stearic acid-d5 | 211443-83-3 | 5 MG
Stearic acid-d5 is a deuterium labeled stearic acid, which is a long-chain dietary saturated fatty acid found in many animal and vegetable fats and oils. It is used as a tracer for quantitation in drug development, with deuteration potentially affecting pharmacokinetic and metabolic profiles of drugs.
- Deuterium labeled stearic acid
- Used as a tracer for quantitation in drug development
- Potential to affect pharmacokinetic and metabolic profiles of drugs
- Store powder at -20°C for 3 years, or 4°C for 2 years
- Store in solvent at -80°C for 6 months, or -20°C for 1 month
Medchemexpress LLC Lactic acid-d3 sodium | 1219802-24-0 | 98% | 5 MG
Lactic acid-d3 sodium is the deuterium labeled form of Lactic acid sodium, an HCAR1 activator and epigenetic modulator. It plays a role as a glycolysis end-product, bridging glycolysis and oxidative phosphorylation. This compound is also recognized as an oncometabolite with an immune protective role in anti-tumor immunity and possesses antimicrobial activity, making it suitable as a food preservative.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Cyclosporin A-d4 | 59865-13-3 | 99.6% | 1 MG
Cyclosporin A-d4 is the deuterium labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant that binds to cyclophilin and inhibits the phosphatase activity of calcineurin with an IC50 of 5 nM. It also inhibits CD11a/CD18 ad.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules, primarily as tracers for quantitation during the drug development process.
- Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC 2-Oxazolidinone, 5-[(3,5-dimethylphenoxy-2,4,6-d3)methyl]- | 1192812-66-0 | 98.0% | 5 MG
Metaxalone-d3 is a deuterium-labeled derivative of Metaxalone, an FDA-approved muscle relaxant. It primarily acts on the central nervous system by inhibiting polysynaptic reflex arcs. It also inhibits MAO-A, offering anti-inflammatory and antioxidant effects. Stable heavy isotopes have been incorporated into drug molecules for tracing and can influence drug pharmacokinetics and metabolic profiles.
- Deuterium labeled Metaxalone
- FDA-approved muscle relaxant
- Inhibits polysynaptic reflex arcs
- Inhibits MAO-A, providing anti-inflammatory and antioxidant effects
- Isotopic enrichment of 99.10%
Medchemexpress LLC Benzyl alcohol-d1 (Benzenemethanol-d1) | 14915-25-4 | 95.7% | 100 MG
Benzyl alcohol-d1 is a deuterium-labeled benzyl alcohol. It serves as a tracer and internal standard for quantitative analysis using techniques such as NMR, GC-MS, or LC-MS. Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may affect the pharmacokinetic and metabolic profiles of drugs
- Stable heavy isotopes like deuterium are incorporated into drug molecules for quantitation during drug development
Medchemexpress LLC Tilmicosin-d3 | 2714486-61-8 | 5 MG
Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. It primarily acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis.
- Effective in treating respiratory diseases in livestock such as cattle, sheep, and pigs.
- Possesses immunomodulatory and anti-inflammatory effects.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Nadolol-d9 | 94513-92-5 | MFCD00049405 | 97.0% | 5 MG
Nadolol-d9 is a deuterium labeled Nadolol, functioning as a non-selective and orally active β-adrenergic receptors blocker. It is intended for research use only.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Supports NMR, GC-MS, or LC-MS applications
Sigma Aldrich Fine Chemicals Biosciences Benz[a]anthracene-d12 98 atom % D | 1718-53-2 | MFCD00142458 | 250MG
Benz[a]anthracene-d12 98 atom % D | Purity: 99% (CP) | Mol Wt: 240.36 | 1718-53-2 | MFCD00142458 | 250MG
Sigma Aldrich Fine Chemicals Biosciences 2-Chlorophenol-3,4,5,6-d4 98 atom % D | 93951-73-6 | MFCD00142898 | 250MG
2-Chlorophenol-3,4,5,6-d4 98 atom % D | Purity: 99% (CP) | Mol Wt: 132.58 | 93951-73-6 | MFCD00142898 | 250MG